Green Bay Packers
Main article: 2010 Green Bay Packers season
The Green Bay Packers finished the season with a 10–6 record and became the first number 6-seeded team in the NFC to compete in the Super Bowl. They are only the second number 6 seeded team to reach the Super Bowl, with the only other number 6 seed to accomplish this feat being the Pittsburgh Steelers, who won Super Bowl XL following the… More 2005 season. Green Bay also joined the 2005 Steelers as the only teams ever to defeat the top three seeded teams on the road in the playoffs. In order to secure their fifth Super Bowl bid they defeated their longtime rivals, the Chicago Bears, in the NFC Championship Game at Soldier Field.

The offense was led by quarterback Aaron Rodgers, who was in his third year as a starter after taking over for the team's all-time leading passer Brett Favre. Rodgers finished the season completing 65.7% of his passes for 3,922 yards and 28 touchdowns, with only eleven interceptions, giving him his second consecutive season with a triple digit passer rating (101.2). He was also a good rusher, adding 356 yards and 4 touchdowns on the ground. His top target was pro bowl receiver Greg Jennings, who caught 76 passes for 1,265 yards and 12 touchdowns, giving him a 16.6 yards per catch average while also ranking him fourth in the NFL in yards and second in touchdown catches. Other reliable targets included receivers James Jones (50 receptions, 676 yards, 5 touchdowns), Donald Driver (51 receptions, 565 yards, 4 touchdowns), and Jordy Nelson (45 receptions, 582 yards, 496 kick return yards). The Packers lost star tight end Jermichael Finley (21 receptions 301 yards, 1 touchdown) to injury in week five who was their leading receiver at the time. The Packers ground game was crippled by injuries, especially the Week 1 loss of Ryan Grant, who had rushed for over 1,200 yards in each of the last two seasons. In his absence, the team relied prominently on Brandon Jackson, who rushed for 703 yards and caught 43 passes for 342, and fullback John Kuhn, who added 281 yards on the ground. The team's offensive line was anchored by pro bowl tackle Chad Clifton, an 11-year veteran.

The Packers defense ranked second in the league in fewest points allowed per game (15). The line was led by Cullen Jenkins, who recorded seven sacks in just eleven games, and 338-pound defensive tackle B. J. Raji, who had 6.5. The linebackers were led by pro bowler Clay Matthews and A. J. Hawk. Matthews ranked fourth in the NFL with 13.5 sacks, while Hawk led the team in combined tackles (111) and intercepted three passes. Three of the Packers starters in the secondary had made the pro bowl. Tramon Williams led the team with a career-high 6 interceptions, while adding 326 punt return yards. Other pro bowl selections included safety Nick Collins (4 interceptions and 70 combined tackles) and hard hitting 13-year veteran cornerback Charles Woodson, who recorded 92 total tackles and forced five fumbles, while also intercepting two passes.

The Packers entered the Super Bowl never having trailed by more than 7 points at any point during the season—a feat that had never been accomplished during a complete season in the Super Bowl era. The last team to complete a season with this distinction was the Detroit Lions in 1962.[13] In the Super Bowl game itself, the Packers never trailed.

Of note, this was Green Bay's first Super Bowl against an AFC team that was not one of the "Original 8" American Football League franchises. The Packers had played Kansas City, Oakland, New England, and Denver in their four previous Super Bowl match-ups, winning against all but Denver. The Steelers, like the Packers, predated the AFL's launch, having begun play in 1933 (12 years after the Packers joined the NFL after two years as an independent team), and moved to the AFC in 1970 as a result of the AFL–NFL merger to even out the two conferences.

Playoffs
Main article: 2010–11 NFL playoffs
Pittsburgh advanced to the Super Bowl with two close wins in the playoffs. After a first-round bye, the Steelers defeated their division rival, the number 5 seeded Baltimore Ravens 31–24, with Ben Roethlisberger's 58-yard completion to Antonio Brown on third down and 19 setting up Rashard Mendenhall's game winning 2-yard touchdown run with 1:33 left in the game. Roethlisberger finished with 226 passing yards and two touchdowns, while the defense forced three turnovers and sacked Baltimore QB Joe Flacco five times, three by James Harrison. Less